Methicillin

From Academic Kids

Methicillin chemical structure
Methicillin

6-((2,6-dimethoxybenzoyl)amino)-
3,3-dimethyl-7-oxo-,(2S-(2alpha,5alpha,6beta))-
4-thia-1-azabicyclo(3.2.0)heptane-
2-carboxylic acid
CAS number
61-32-5
ATC code
J01CF03
Chemical formula C17H20N2O6S
Molecular weight 380.419
Bioavailability  ?
Metabolism  ?
Elimination half-life  ?
Excretion  ?
Pregnancy category  ?
Legal status  ?
Routes of administration Intravenous

Methicillin is an antibiotic related to penicillin and other beta-lactam containing antibiotics. It is often used to treat infections caused by bacteria carrying an antibiotic resistance, e.g., staphylococci. As methicillin is deactivated by gastric acid, it has to be administered by injection.

Uses

Methicillin is not commonly used in clinical practice, but serves a purpose in the laboratory to determine antibiotic sensitivity in microbiological culture.

"Methicillin-resistant Staphylococcus aureus" (MRSA) is a strain of staphylococcus that is resistant to methicillin and related compounds.

External links

  • ChemBank entry (http://chembank.med.harvard.edu/bioactives/display.html?compound_id=762)
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